March 6, 2020
TIGL received NIH funding to join the formation of the Immuno-Engineering to Improve Immunotherapy (i3) Center with Harvard University's Wyss Institute of Biologically Inspired Engineering and its collaborating institutions, the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS), and Harvard's Department of Stem Cell and Regenerative Biology. DFCI News Release
September 24, 2019
Derin was an invited speaker to ASHI in Pittsburgh, PA to present "The Role of HLAs in Developing Vaccine-Based Immunotherapies"
May 14, 2019
Shuqiang gave a talk at NGS & Clinical Diagnostics USA Congress in Boston, MA titled "Single-cell TCR Sequencing Applied to Neoantigen Vaccination Therapy for Cancer"
Dec 19, 2018
Personal neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial, new study shows. DFCI News Release
May 12, 2018
Derin Keskin, TIGL Immunology Lead Scientist, gave a keynote presentation titled ”Neoantigens in cancer immunotherapy” at the 32nd European Immunogenetics and Histocompatibility Conference in Venice Lido, Italy
May 6, 2018
Derin Keskin presented a poster titled “Systematic profiling of HLA-C epitopes” at the AAI Annual Meeting in Austin, TX
April 14-18, 2018
Derin Keskin presented a poster titled “Personal neoantigen-targeting vaccination generates neoepitope-specific T cell responses in tumors of patients with glioblastoma” at the AACR Annual Meeting 2018 in Chicago, IL
October 2017
TIGL awarded a U24 grant as a Cancer Immune Monitoring and Analysis Center
October 4, 2017
Sachet A. Shukla, TIGL Computational Lead Scientist, gave a talk titled “Cancer-germline antigens discriminate clinical outcome to CTLA4 blockade” at the 2017 AACR Tumor Immunology and Immunotherapy Conference in Boston, MA
July 5, 2017
Personal neoantigen vaccine prompts strong anti-tumor response in patients, new study shows. Dana-Farber news release
May 3, 2017
Sachet A. Shukla gave a talk titled “Somatic alterations in HLA genes as an immune escape mechanism in cancer” at the Biomarkers and Immuno-oncology World Congress in Philadelphia, PA
April 2, 2017
Sachet A. Shukla gave a talk titled “Somatic HLA mutations and neoantigen identification for immunotherapy analyses” as part of an educational session at the AACR Annual Meeting in Washington, DC
2016
Sachet A. Shukla receives NIH/NCI R50 award for grant titled “Immunogenomic analytical approaches for research and clinical applications” for 2016-2021